Leonard H Wexler Selected Research

Rhabdomyosarcoma

1/2019	MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification.
1/2019	Worse Outcomes for Head and Neck Rhabdomyosarcoma Secondary to Reduced-Dose Cyclophosphamide.
1/2019	Immunotherapeutic Targeting of GPC3 in Pediatric Solid Embryonal Tumors.
7/2017	A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
2/2017	Paratesticular rhabdomyosarcoma: Importance of initial therapy.
9/2016	Long-term effect of chemotherapy-intensity-modulated radiation therapy (chemo-IMRT) on dentofacial development in head and neck rhabdomyosarcoma patients.
1/2016	Late Toxicities of Intensity-Modulated Radiation Therapy for Head and Neck Rhabdomyosarcoma.
3/2015	Radiation for bone metastases in Ewing sarcoma and rhabdomyosarcoma.
12/2014	Predicting outcome in patients with rhabdomyosarcoma: role of [(18)f]fluorodeoxyglucose positron emission tomography.
11/2014	Rhabdomyosarcoma: current challenges and their implications for developing therapies.

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Leonard H Wexler Research Topics

Disease

31	Neoplasms (Cancer) 01/2021 - 02/2002
25	Rhabdomyosarcoma 01/2019 - 02/2002
13	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 01/2005
11	Ewing Sarcoma (Sarcoma, Ewing) 11/2017 - 01/2005
9	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 06/2005
6	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2006
3	Neuroblastoma 07/2017 - 03/2003
2	Hepatoblastoma 01/2019 - 11/2012
2	Cardiotoxicity 01/2019 - 01/2016
2	Left Ventricular Dysfunction 01/2019 - 01/2016
2	Rhabdoid Tumor (Rhabdoid Tumors) 01/2019 - 01/2008
2	Necrosis 01/2016 - 06/2005
1	Desmoplastic Small Round Cell Tumor 01/2021
1	Alopecia (Baldness) 01/2020
1	Residual Neoplasm 05/2019
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2019
1	Heart Failure 01/2019
1	Ependymoma 07/2017
1	Diffuse Intrinsic Pontine Glioma 07/2017
1	Brain Neoplasms (Brain Tumor) 07/2017
1	Glioma (Gliomas) 07/2017
1	Medulloblastoma 07/2017
1	Melanoma (Melanoma, Malignant) 03/2016
1	Neurofibrosarcoma (MPNST) 01/2016
1	Cataract (Cataracts) 01/2016
1	Disease Progression 04/2015
1	Second Primary Neoplasms (Neoplasms, Second) 01/2015
1	Genetic Translocation (Chromosomal Translocation) 11/2014
1	Ascites 09/2014
1	Cranial Nerve Diseases (Cranial Nerve Disorders) 01/2013
1	Adenocarcinoma 11/2010
1	Adenocarcinoma of Lung 11/2010

Drug/Important Bio-Agent (IBA)

4	Methotrexate (Mexate)FDA LinkGeneric 01/2016 - 06/2005
4	Irinotecan (Camptosar)FDA LinkGeneric 02/2013 - 02/2002
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 11/2012
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 04/2011
3	DNA (Deoxyribonucleic Acid)IBA 11/2017 - 11/2014
2	Biological ProductsIBA 01/2022 - 01/2019
2	Protons (Proton)IBA 01/2020 - 07/2015
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2019
2	Dexrazoxane (Zinecard)FDA LinkGeneric 01/2019 - 01/2016
2	AnthracyclinesIBA 01/2019 - 01/2016
2	Cisplatin (Platino)FDA LinkGeneric 01/2016 - 04/2011
2	Ifosfamide FDA LinkGeneric 01/2016 - 04/2015
2	Pharmaceutical PreparationsIBA 07/2014 - 11/2012
2	Carboplatin (JM8)FDA LinkGeneric 02/2013 - 01/2009
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2012 - 03/2003
2	LigandsIBA 11/2012 - 03/2003
2	Interferon-gamma (Interferon, gamma)IBA 11/2009 - 03/2003
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021
1	Type 4 Fibroblast Growth Factor ReceptorIBA 01/2021
1	TESIBA 01/2020
1	Cyclin D1IBA 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	pro-brain natriuretic peptide (1-76)IBA 01/2019
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019
1	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2019
1	GlypicansIBA 01/2019
1	CateninsIBA 01/2019
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2019
1	MTOR InhibitorsIBA 07/2017
1	temsirolimus FDA Link 07/2017
1	perifosineIBA 07/2017
1	dipinacoline glutamateIBA 07/2017
1	ParaffinIBA 01/2017
1	Cell-Free Nucleic AcidsIBA 01/2017
1	Formaldehyde (Formol)FDA Link 01/2017
1	IpilimumabIBA 03/2016
1	Immune Checkpoint InhibitorsIBA 03/2016
1	Lysine (L-Lysine)FDA Link 01/2016
1	Growth Hormone (Somatotropin)IBA 01/2016
1	microbial alkaline proteinase inhibitor (MAPI)IBA 01/2016
1	Etoposide (VP 16)FDA LinkGeneric 01/2016
1	Histones (Histone)IBA 01/2016
1	IntegrinsIBA 11/2015
1	RNA-Binding Protein EWSIBA 07/2015
1	Transcription Factors (Transcription Factor)IBA 06/2014
1	Insulin-Like Growth Factor Binding Protein 2IBA 04/2014
1	Insulin-Like Growth Factor Binding Protein 3IBA 04/2014
1	Insulin (Novolin)FDA Link 04/2014
1	Insulin-Like Growth Factor I (IGF-1)IBA 04/2014
1	Complementary DNA (cDNA)IBA 06/2013
1	IceIBA 01/2013
1	lexatumumabIBA 11/2012
1	Monoclonal AntibodiesIBA 11/2012
1	Pamidronate (Aredia)FDA LinkGeneric 04/2011
1	Temozolomide (Temodar)FDA LinkGeneric 12/2009

Therapy/Procedure

18	Therapeutics 01/2020 - 03/2003
17	Radiotherapy 05/2019 - 01/2003
13	Drug Therapy (Chemotherapy) 11/2017 - 02/2004
3	Adjuvant Chemotherapy 07/2015 - 02/2004
2	Aftercare (After-Treatment) 11/2017 - 11/2010
2	Induction Chemotherapy 01/2016 - 12/2014
2	Brachytherapy 07/2015 - 10/2014
1	Proton Therapy 01/2019
1	Immunotherapy 01/2019
1	Neoadjuvant Therapy 11/2016
1	Orbital Implants 07/2015
1	Trachelectomy 04/2009